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What are peripheral neuropathies?

Sandeep Dhanyamraju MD
Medically reviewed by Sandeep Dhanyamraju
Sandeep Dhanyamraju MD
Medically reviewed by Sandeep Dhanyamraju

Peripheral neuropathies are a pathology of the nervous system that occurs against the background of damage to peripheral nerves due to compression or injury and is not inflammatory. When several nerves located in the same area are affected, the term “polyneuropathy” is used.

Up to 15% of the adult population suffers from various manifestations of neuropathy. Presumably, the number of patients with the disease is higher because some people do not go to the doctor with initial manifestations.

Causes of neuropathy

To date, the exact cause of peripheral neuropathies has not been established. The emergence and development of the disease are influenced by many factors, such as diabetes mellitus, HIV infection, chronic alcoholism, organic diseases, and external factors. In addition, forms of hereditary pathology associated with genetic defects are distinguished.

Internal pathologies that can affect the development of neuropathy:

  • endocrine diseases;
  • avitaminosis;
  • autoimmune diseases;
  • multiple sclerosis;
  • rheumatoid arthritis.
  • External factors include:
  • trauma;
  • intoxication;
  • infections;
  • alcoholism.

Depending on the causes of occurrence, peripheral neuropathies are classified:

  • post-traumatic – appears as a result of injuries of the nerve fiber and its branches (with bruises, cuts, dislocations, fractures). In most clinical cases, this form of the disease affects the ulnar nerve, facial, sciatic, nerves of the lower extremities;
  • diabetic – develops with diabetes mellitus;
  • ischemic – develops as a result of compression of nerve bundles in the spine or muscle-bone joints. As a result, the blood supply to the nerve endings is disrupted. It develops against the background of vascular diseases and with large blood loss. In most cases, the optic nerve is affected;
  • alcoholic – occurs due to the use of large doses of alcohol, the decay products of which complicate the metabolic process.

Symptoms of neuropathy

Symptoms of neuropathy

The disease manifests itself in different ways. The most characteristic symptoms of neuropathic pain  are:

  • violation of the sensitivity of the damaged area;
  • pain syndrome of varying severity and intensity;
  • muscle weakness;
  • spasms and cramps;
  • Difficulty moving.


Neuropathy is considered a rather difficult condition to diagnose. The disease may not make itself felt for a long time and may not show up with specific symptoms. Therefore, the doctor needs to collect a complete history to make the correct diagnosis.

At the reception, the patient needs to tell the neurologist about their lifestyle to inform whether and what medications were taken, if viral diseases were transferred, whether there are chronic and hereditary pathologies, and whether surgical treatment was carried out. After an oral questioning, the doctor examines the patient; palpation of the nerve trunks is mandatory, revealing soreness and thickening along their course. Beating on the nerve endings is carried out, and tingling sensations are detected in the sensitive area. Next, the patient needs to undergo a series of instrumental examinations and laboratory tests:

  • clinical and biochemical blood test;
  • elastography;
  • ultrasound procedure;
  • CT scan;
  • electromyography;
  • MRI and X-ray;
  • consultation of related specialists (ophthalmologists).

Numerous and confusing anatomical variants of the peripheral nervous system make it difficult to understand its structure, so only a highly qualified specialist can diagnose the disease. The best neurologist with many years of practice work in our center FNKTs FMBA. Modern equipment and our clinical diagnostic center allow us to quickly and accurately identify the problem, which speeds up the process of starting treatment. Prompt response to the issue helps avoid irreparable processes in the body and exclude the development of pathology.


The main task of prevention is the timely treatment of infectious and systemic diseases. Patients with diabetes mellitus and other predisposing pathologies need to visit a doctor regularly and strictly follow their prescriptions and recommendations. The rest of the prevention measures are reduced to simple rules:

  • give up addictions;
  • lead an active lifestyle with moderate physical activity;
  • follow the correct and balanced diet;
  • wear comfortable clothing and shoes that do not compress your feet and ankles;
  • spend more time outdoors and hiking.

How to treat pain neuropathy?

How to treat pain neuropathy

In the multidisciplinary center of the FNKTs FMBA, therapy is always carried out comprehensively with simultaneous treatment of the concomitant disease that caused the neuropathy. After a thorough diagnosis, the neurologist determines the tactics of treatment depending on the form of the disease, the severity of its course, and the reasons that provoked the lesion of neuromuscular conduction.

Treatment is always consistent. Initially, the damaging factor (compression) is eliminated, then inflammation and pain are relieved, the complete functioning of the affected area is restored, and regenerative processes are stimulated. Prescribed drug treatment includes the use of anti-inflammatory, antiviral, pain relievers, and other drugs, including those that improve nerve patency. A course of vitamins may be indicated for drug therapy.

Physiotherapy shows positive results in treatment:

  • physiotherapy;
  • electrophoresis;
  • magnetotherapy;
  • laser therapy;
  • hydrotherapy;
  • massage;
  • acupuncture.

When drug therapy is insufficient, the neurologist refers the patient to a neurosurgeon. FNKTS FMBA offers modern and effective surgical treatment:

  • prosthetics or nerve plastics;
  • neurolysis;
  • negotiation;
  • transposition of tendons and muscles.
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Edward Medina
Edward Medina
15:34 30 Jun 22
Just such an amazing staff that makes you feel like part of their family. I’ve been going there for over 5 years now... and each visit I get the very best care and treatments that I have ever received in the 20+ years that I’ve been dealing with severe debilitating migraines. Since i started seeing them the number of my migraines has dropped from 15-20 a month to 2-3 every 3 month. I highly recommend them …they will change your life!read more
Daneisha Johnson
Daneisha Johnson
22:20 19 May 22
Dr. Askari was very kind and explained everything so I could understand. The other staff were nice as well. I would... have gave 5 stars but I was a little taken aback when I checked in and had to pay 600.00 upfront. I think that should have been discussed in a appointment confirmation call or email just so I could have been more
Jean Cooper
Jean Cooper
16:54 29 Apr 22
I love the office staff they are friendly and very helpful. Dr. JODIE is very caring and understanding to your needs... and wants to help you. I will go back. would recommend Dr. Dr. Jodie to other Patients in a heart beat. The team works well more
Linda M
Linda M
19:40 02 Apr 22
I was obviously stressed, needing to see a neurologist. The staff was so patient and Dr. Ansari was so kind. At one... point he told me to relax, we have time, when I was relaying my history of my condition. That helped ease my stress. I have seen 3 other neurologists and he was the only one who performed any assessment tests on my cognitive and physical skills. At one point I couldn't complete two assessments and got upset and cried. I was told, it's OK. That's why you're here. I was truly impressed, and super pleased with the whole experience!read more
Leslie Durham
Leslie Durham
15:05 01 Apr 22
I've been coming here for about 5 years. The staff are ALWAYS friendly and knowledgeable. The Doctors are the absolute... best!! Jodie Moore is always in such a great mood which is a plus when you are already stressed. Highly recommendedread more
Monica Del Bosque
Monica Del Bosque
14:13 25 Mar 22
Since my first post my thoughts have changed here. It's unfortunate. My doctor and PA were great, but the office staff... is horrible. They never call you back when they say they will, they misinform you, they cause you too much stress wondering what's going on, they don't keep you posted. They never answer the phone. At this point I've left four messages in the last week, and I have sent three messages. Twice from their portal and one direct email. No response. My appointment is on Monday morning at 8:30am, no confirmation on my insurance and what's going on. What the heck is going on, this is ridiculous!I've given up... the stress her office staff has put me through is just not worth it. You can do so much better, please clean house, either change out your office staff, or find a way for them to be more efficient please. You have to do something. This is not how you want to run your practice. It leaves a very bad impression on your more
Ron Buckholz
Ron Buckholz
23:32 23 Mar 22
I was actually pleasantly surprised with this visit! It took me a long time to get the appointment scheduled because no... one answers your phones EVER! After a month, I finally got in, and your staff was warm, friendly, and I was totally impressed! I feel like you will take care of my needs!read more
Steve Nabavi
Steve Nabavi
16:28 16 Mar 22
It was a nice visit. Happy staff doing all they can do to comfort the patients in a very calming environment. You ask... me they are earned a big gold star on the fridge. My only complaint they didn't give me any more
Katie Lewis
Katie Lewis
16:10 10 Feb 22
Had very positive appointments with Jodie and Dr. Sheth for my migraine care. Jodie was so fast with the injections and... has so much valuable info. I started to feel light headed during checkout and the staff was SO helpful—giving me a chair, water, and taking me into a private room until I felt better. Highly recommend this practice for migraine patients, they know what they’re doing!!read more
Joshua Martinez
Joshua Martinez
16:02 10 Dec 21
I was scheduled to be checked and just want to say that the staff was fantastic. They were kind and helpful. I was... asked many questions related to what was going on and not once did I feel as though I was being brushed off. The front desk staff was especially great in assisting me. I'm scheduled to go back for a mri and am glad that I'll be going more
Isabel Ivy
Isabel Ivy
21:42 03 Nov 21
I had such a good experience with Lone Star Neurology, Brent my MRI Tech was so awesome and made sure I was very... comfortable during the appointment. He gave me ear plugs, a pillow, leg support and blanket, easiest MRI ever lol 🤣 My 72 hour EEG nurse Amanda was also so awesome. She made sure I was take care of over the 3 days and took her time with the electrodes to make sure it was comfortable for me! Paige was also a huge help in answering all my questions when it came to my test results, and letting me know her honest opinions about how I should go forth with my more
Leslie Luce
Leslie Luce
17:37 20 Oct 21
The professionalism and want to help attitude of this office was present from the moment I contacted them. The follow... up and follow through as well as their willingness to find a way to schedule my dad was above and beyond. We visited two offices in the same day with the same experience. I am appreciative of this—we spend a lot of time with doctors and this was top notch start to more
robert Parker
robert Parker
16:38 16 Apr 21
I love going to this office. The staff is friendly and helpful. The doctor is great. I am getting the best... neurological tests and treatment I have ever had. The only reason I did not give them a 5 star rating is because it is impossible to reach a live person at the office to reschedule appointments. Every time I have tried to get through to the office it says all people are busy and I am sent to a voicemail. If they could get their phone answering fixed, I would give them a strong 5 more
MaryAnn Hornbaker
MaryAnn Hornbaker
00:26 25 Feb 21
Dr. Harney is an excellent Dr. I found him friendly , personable and thorough. I evidently am an unusual case. ... Therefore he spent a Hugh amount of time educating me. He even gave me literature to further explain my condition and how to follow up. This is something you rarely get from your doctors. So I am more than please with my doctor and his more
Roger Arguello
Roger Arguello
03:05 29 Jan 21
Always courteous, professional. The staff is very friendly and always work with you to find the best appointment time.... The care team has been great. Always taking the time to listen to your concerns and to find the best more
Margaret Rowland
Margaret Rowland
01:12 27 Jan 21
I have been a patient at Lone Star Neurology for several years. Now both my adult daughters also are patients there. I... love Jodie. She is always so prompt whether it is a teleamed call are a visit in the office. She takes the time to explain everything to me and answers all my questions. I am so blessed to have Jodie as my more
Susan Miller
Susan Miller
03:01 13 Jan 21
My husband had an accident 5 years ago and Lone Star Neurology has been such a blessing to us with my husbands care.... Jodie Moore is his provider and she is amazing! Jodie is very knowledgeable, caring, and thorough. She takes her time with you, making sure your needs are met and she is happy to answer any questions you may have. Lone Star Neurology’s patients are very lucky to have Jodie providing their care. Thank you Lone Star Neurology and especially Jodie for everything you have done for us. Jodie, you are the best!read more
Windalyn C
Windalyn C
01:32 09 Jan 21
Jodie is wonderful. She is very caring and knowledgeable. I have been to over a dozen neurologists, and none were able... to help me as much as they have here. Thanks!read more
Katie Kordel
Katie Kordel
00:40 09 Jan 21
Jodi Moore, nurse practitioner, is amazing. I have suffered from frequent, debilitating headaches for almost 20 years.... She has provided the best proactive and responsive care I have ever received. My quality of life has been greatly improved by her caring approach and tenacity in finding more
Ellie Natsis
Ellie Natsis
15:41 07 Jan 21
I have had the best experience at this neurologist's office! For over a year I have been receiving iv treatments here... each month and my nurse, Bobbie is beyond wonderful!! She's so attentive, knowledgeable, caring, and detail oriented. She makes an otherwise uncomfortable experience much more pleasant and definitely puts me at ease! She also helps me with my insurance,ordering this specialty medication and dealing with the ordering process which is no easy feat.Needless to say, she goes above a beyond in every way and I'm so grateful to this office and to Bobbie for all they do for me!read more
Matt Morris
Matt Morris
15:39 07 Jan 21
Let me start by saying that I have been coming here for years. Due to my autoimmune disease, I am in this office... once every three weeks for multiple hours at a time. The office is very clean and the staff very friendly. My only complaint would be there communication via phone. They aren't the best at responding if you leave a voicemail and expect a call back. I understand that this is prob just due to the sheer number of alls they receive daily. What I can say I like the best about the office are the people. Bobby who handles my infusions is great. I never have any issues with her setting up my infusions. She is very quick to reply to messages sent via text and if she were to leave then my whole opinion of the office may change. I also enjoy people like Matt, Lauren, and Jodi. I appreciate all that they do for me and without this team I'm not sure I would be as happy as I am to visit the office as frequently as I have to. Please ensure that these folks are recognized as they are what makes my visit to this office so tolerable :).read more
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