Abbvie - Upper Limb Essential Tremor Study - Botox

Living with shaky hands is far more than a minor inconvenience. For millions of people, it is a daily struggle that turns ordinary moments – writing a note, holding a glass, fastening a button – into exhausting challenges. If you have been searching for a more effective way to manage these symptoms, Lone Star Neurology in Texas is preparing to offer a significant advancement in patient care. Beginning in August 2026, we will be hosting an essential tremor Botox study sponsored by AbbVie. This upcoming research, formally designated the AGN-151607-DP study, is a double-blind, placebo-controlled trial designed to evaluate the effectiveness of a specialized form of botulinum toxin for adults dealing specifically with hand and arm tremors.

The primary objective of this essential tremor clinical trial is to assess the safety and efficacy of a novel investigational injection in a rigorously controlled clinical environment. If traditional oral medications have failed to deliver sufficient relief – or if their side effects have become difficult to tolerate – this study may represent exactly the opportunity you have been waiting for. We are currently inviting patients to register their interest early, ensuring they are first in line when enrollment opens this summer. By participating, you are not only seeking meaningful relief for yourself – you are helping the entire medical community find a better path forward for everyone living with ET. Call us at 214-619-1910 to register your interest today.

What Is Upper Limb Essential Tremor?

Essential tremor is frequently dismissed as simple nervousness or a natural consequence of aging. In reality, it is a legitimate neurological condition causing involuntary, rhythmic shaking – most commonly in the hands and arms. When these tremors predominantly affect the upper extremities, physicians classify the condition as upper limb essential tremor.
This distinction from Parkinson’s disease is clinically important. Parkinson’s tremors typically occur at rest, when the muscles are inactive.

Essential tremor, by contrast, is an “action tremor” – meaning the shaking intensifies precisely when you are attempting to use your hands. Consider the small daily moments most people take entirely for granted:

Buttoning a shirt in the morning
Holding a spoon without spilling its contents
Writing a signature on a check
Applying makeup or shaving with precision

When upper limb essential tremor is present, each of these tasks becomes an exhausting hurdle. The condition is not only physically limiting – it is emotionally isolating. Many patients gradually withdraw from social situations out of embarrassment, quietly pulling away from the people and activities they love most. Our hands are our primary tools for engaging with the world, which is precisely why finding a targeted tremor treatment near me that works directly on the muscles involved has become one of the highest priorities in movement disorder research today.

About the AbbVie Botox ET Study

The field of movement disorder medicine is continually seeking more precise, targeted interventions – treatments that can quiet tremors in specific muscle groups without broadly affecting the rest of the body. This is exactly what makes the upcoming AbbVie essential tremor research study so significant.

This trial is a multicenter, randomized, double-blind study – the gold standard of clinical research design. “Double-blind” means that neither the participant nor the treating physician knows who is receiving the active study drug and who is receiving the placebo during the initial phase, ensuring the results are entirely free from bias. The study is structured as a two-arm parallel-group design that ultimately transitions into an open-label period, during which participants can receive the active treatment.

The investigational drug, AGN-151607-DP, is a specialized formulation of Botox for tremor control. Researchers aim to determine whether targeted injections into the overactive muscles of the arm and hand can produce meaningful, sustained reductions in tremor severity. The full study duration is approximately 72 weeks – a timeline specifically designed to evaluate not only whether the Botox tremor treatment works, but how long its effects persist and how safe it is for extended use.

Who May Be Eligible?

While not every patient with a tremor will meet the specific requirements of this trial, the eligibility criteria are intentionally broad, designed to include a wide range of adults. The foundational requirements for the hand tremor Botox study are as follows:

Age range. You must be between 18 and 85 years old.
Confirmed diagnosis. You must have a formally established diagnosis of Essential Tremor meeting the modified Tremor Research Investigation Group (TRIG) criteria.
Upper limb involvement. The study is specifically focused on individuals whose tremors primarily affect the hands or arms.

These represent only the initial screening parameters. Once the enrollment period opens, our clinical team will conduct a comprehensive individual assessment that includes a review of your medical history, current medications, and tremor severity. The study’s principal investigator determines final eligibility to ensure both participant safety and the integrity of the research data.

What to Expect as a Study Participant

If you choose to enroll, your participation will be carefully structured over approximately 18 months. The process begins with a screening visit during which our team reviews your health history and confirms that you meet all enrollment criteria. Once accepted, you will enter the randomization phase and receive your first essential tremor injection in the affected limb under specialist supervision.

The study experience is organized and thoroughly supported throughout:

Initial injections. You receive either the active study drug or a placebo administered in a controlled clinical setting.
Regular monitoring. You return for scheduled follow-up visits at which our board-certified neurologists assess hand strength, tremor reduction, and overall well-being.
Open-label period. Later in the study, participants transition to a phase in which the active Botox tremor treatment is administered, ensuring all enrollees ultimately have access to the investigational therapy.
Expert oversight. You are never navigating this alone. Our team monitors every participant with exceptional care throughout the study.

Benefits and Risks of Participation

Joining a clinical trial is a meaningful decision – one that comes with genuine potential rewards and considerations that deserve transparency.

Potential benefits include:

Early access to a cutting-edge essential tremor Botox formulation that is not yet available to the general public
A high level of specialized medical monitoring and neurological care at absolutely no cost to you
The deeply meaningful contribution of advancing an essential tremor research study that could transform treatment options for millions of people worldwide

Potential risks to be aware of:

As with any injection-based procedure, participants may experience temporary soreness, bruising, or redness at the needle site
Specific to Botox for tremor therapy, there is a possibility of transient muscle weakness in the treated hand or arm – a known and carefully monitored effect
As with all investigational treatments, the degree of symptom improvement cannot be guaranteed in advance

The extended 72-week study duration exists specifically to allow researchers to identify the optimal balance between effective tremor suppression and preserved hand function. Our coordinators will review every potential side effect with you in comprehensive detail before any commitment is made, ensuring you can make a fully informed decision with complete confidence.

How to Register Interest - Contact Lone Star Neurology

We know that many patients across Dallas-Fort Worth and throughout Texas have been searching for a clinical trial near me after finding inadequate relief from conventional oral therapies. The AbbVie study at Lone Star Neurology is a coming-soon opportunity that is very much worth securing your place in. Official patient visits are expected to begin in August 2026 – but registering your interest now ensures that you are contacted directly the moment enrollment opens.

To register, complete the “Click to Apply” form on our website. The form is brief and straightforward, asking for:

Your name and contact information
Your date of birth (to verify the 18-85 age range)
Confirmation that you have received an ET diagnosis from a physician

If you would prefer to speak with a member of our team directly, or if you have specific questions about this tremor treatment near me, please do not hesitate to call.

Contact Lone Star Neurology:

Phone: 214-619-1910
Location: Texas – Multiple DFW Locations

Do not let a tremor define your life or limit the moments that matter most. Take the first step toward steadier hands and register your interest with the AbbVie essential tremor clinical trial community at Lone Star Neurology today. We look forward to helping you move forward with confidence.