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Myopathy: Symptoms and Causes

Sandeep Dhanyamraju MD
Medically reviewed by Sandeep Dhanyamraju
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Sandeep Dhanyamraju MD
Medically reviewed by Sandeep Dhanyamraju

Human muscles are essential for performing daily tasks. With the help of muscles, we move, take objects and even smile. But there are groups of diseases that can affect the muscles. One such disease is myopathy.

This serious disease can greatly affect muscle function. Besides, the disease also affects the appearance of the patient. Such a disease can significantly impair a person’s daily routine. And it can lead to the occurrence of psychological diseases.

In our article, we will tell you about what myopathy is. We will also tell you about the symptoms of the disease. And also we will show you the types and causes of this condition. Read our article to the end to gain the necessary knowledge and be able to distinguish this disease. This will help you if you experience symptoms and early signs of myopathy.


What Is Myopathy?

It is a serious condition. It belongs to a type of muscle disease. There are many types of conditions today. All of them affect the muscles and their work in different ways. But this serious disease generally leads to the same frequent effects. These effects are weakening and wasting of the muscles.

As a result, the effects can adversely affect a person’s daily routine. Due to the disease, the patient can barely move normally. This leads to the fact that the daily routine becomes difficult for a person with the condition.

The disease also often leads to psychological problems. This is because the disease often affects a person’s appearance. This causes discomfort in the patient. And it leads to the development of depression and low self-esteem. That is why therapy should include a set of measures. They are to prevent negative effects and complications.


Symptoms of Myopathy

myopathy symptoms

It is a group of muscle disorders. It can cause weakness, wasting, and sometimes pain in the muscles. The symptoms can range from mild to severe. And they can vary depending on the underlying cause of the condition:


  1. Muscle weakness. One of the most common symptoms is weakness, which can range from mild to severe. This can affect one or many muscle groups. And it can make it difficult to perform everyday activities.
  2. Fatigue. People with the disease may experience fatigue and tiredness, even after minimal physical activity. This can result from the muscles not receiving enough oxygen and nutrients. This causes them to tire easily.
  3. Pain. Some experience muscle pain, ranging from a dull ache to sharp, stabbing pain. This pain may be present at rest or when the muscles are used.
  4. Cramping. It is a common symptom of myopathy, especially after physical activity. An imbalance of electrolytes in the muscle fibers can cause this. This leads to an abnormal contraction of the muscle.
  5. Stiffness. People may experience stiffness in their muscles, making it difficult to move. This stiffness may worsen in the morning and improve as the day progresses.
  6. Muscle wasting. Over time, the condition can cause muscle wasting. The muscles can shrink and become smaller in size. This can result in a visible reduction in muscle mass and muscle strength.
  7. Muscle twitching. Some individuals may experience muscle twitching or spasms. It can be a sign of nerve damage or muscle damage.


In conclusion, the symptoms can vary greatly. But this depends on the underlying cause of the condition.


What Causes Myopathy

The common causes include:


  1. Inherited genetic mutations. Some forms are inherited and caused by mutations in specific genes.
  2. Trauma or injury. Physical trauma or injury to the muscles can result in a condition.
  3. Inflammatory conditions. Certain conditions like polymyositis or dermatomyositis cause muscle weakness and lead to disease.
  4. Endocrine disorders. Hormonal imbalances in thyroid disease or adrenal gland disorders result in disease.
  5. Infections. Certain infections, such as Lyme disease or human immunodeficiency virus (HIV), are other things that cause myopathy.
  6. Toxins and medications. Certain toxins and medications, such as alcohol or statins, result in muscle damage.
  7. Nutritional deficiencies. A lack of certain nutrients like vitamin D or carnitine results in muscle weakness.


It’s important to note that the cause may not be known in some cases. Consultation with a doctor is necessary for an accurate diagnosis and treatment plan.


Myopathy Types

myopathy types

Myopathy is a broad term that refers to a group of disorders. There are many different types of myopathy muscle disease. Each has its specific symptoms and underlying causes. Some of the most common types of the condition include:


  • Duchenne Muscular Dystrophy (DMD). DMD is an X-linked genetic disorder that primarily affects boys. It causes progressive muscle weakness. It’s especially in the legs and pelvis. And it can lead to mobility problems, difficulty breathing, and heart problems.
  • Limb-Girdle Muscular Dystrophy (LGMD). It is a group of genetic disorders that primarily affect the muscles of the hips and shoulders.
  • Becker Muscular Dystrophy (BMD). This is a less severe form of muscular dystrophy that is also caused by a genetic mutation. It causes progressive muscle weakness. But it happens at a slower rate than DMD and may not become clear until later in life.
  • Polymyositis. Polymyositis is an autoimmune disorder that causes inflammation of the skeletal muscles. It can lead to progressive muscle weakness, difficulty swallowing, and breathing problems.
  • Dermatomyositis. It is another autoimmune disorder that causes muscle weakness as well as a skin rash. The rash can be associated with photosensitivity (sensitivity to sunlight). And it can lead to red, scaly patches on the skin.
  • Mitochondrial. Those are a group of disorders caused by abnormalities in the mitochondria. They are the structures in the cells that produce energy. These disorders can cause muscle weakness, fatigue, and problems with the heart, and brain.
  • Centronuclear. They are a group of genetic disorders causing muscle weakness and wasting. It’s especially in the muscles of the face, neck, and limbs.
  • Congenital. They are present at birth and cause muscle weakness and wasting. Some types of congenital myopathy muscle disease may also cause heart problems.
  • Endocrine. They’re caused by a problem with the hormones that regulate metabolism. These disorders can cause muscle weakness and wasting. And they can also affect the heart, brain, and other organs.
  • Inflammatory. They are a group of disorders that are caused by an immune system attack on the muscle fibers. Some of the most common types of the inflammatory condition include polymyositis and dermatomyositis.


Bottom Line 

As you can see, myopathy is a serious disease for any person. And the signs of myopathy can vary from person to person. That is why it is very important to look for competent and modern methods of treating the disease. You can rule out complications and a debilitating condition with the right therapy. And the normal life cycle may return soon.



  • Is myopathy curable?

Some types of myopathy can occur due to genetic mutations, and they can be uncurable. But other types of myopathy may be treatable with:

  • Medications.
  • Physical therapy.
  • Lifestyle changes.


  • What are the signs of myopathy?

The signs of myopathy can vary depending on the underlying cause and severity. Common signs include muscle weakness, muscle wasting, and fatigue. Some people with myopathy may also experience muscle pain, cramping, and stiffness.

  • How do you know if you have myopathy?

You must see a doctor for a diagnosis if you are experiencing muscle weakness, wasting, or pain. Your doctor may order tests such as a muscle biopsy, electromyography, or blood test. They are to determine the cause of your symptoms and diagnose myopathy.

  • What does muscle myopathy feel like?

Some experience muscle cramping, stiffness, and a feeling of heaviness in their muscles. The severity of the symptoms can vary. It depends on the underlying cause and the extent of muscle damage.

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Just such an amazing staff that makes you feel like part of their family. I’ve been going there for over 5 years now... and each visit I get the very best care and treatments that I have ever received in the 20+ years that I’ve been dealing with severe debilitating migraines. Since i started seeing them the number of my migraines has dropped from 15-20 a month to 2-3 every 3 month. I highly recommend them …they will change your life!read more
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Dr. Askari was very kind and explained everything so I could understand. The other staff were nice as well. I would... have gave 5 stars but I was a little taken aback when I checked in and had to pay 600.00 upfront. I think that should have been discussed in a appointment confirmation call or email just so I could have been more
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I was obviously stressed, needing to see a neurologist. The staff was so patient and Dr. Ansari was so kind. At one... point he told me to relax, we have time, when I was relaying my history of my condition. That helped ease my stress. I have seen 3 other neurologists and he was the only one who performed any assessment tests on my cognitive and physical skills. At one point I couldn't complete two assessments and got upset and cried. I was told, it's OK. That's why you're here. I was truly impressed, and super pleased with the whole experience!read more
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I've been coming here for about 5 years. The staff are ALWAYS friendly and knowledgeable. The Doctors are the absolute... best!! Jodie Moore is always in such a great mood which is a plus when you are already stressed. Highly recommendedread more
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14:13 25 Mar 22
Since my first post my thoughts have changed here. It's unfortunate. My doctor and PA were great, but the office staff... is horrible. They never call you back when they say they will, they misinform you, they cause you too much stress wondering what's going on, they don't keep you posted. They never answer the phone. At this point I've left four messages in the last week, and I have sent three messages. Twice from their portal and one direct email. No response. My appointment is on Monday morning at 8:30am, no confirmation on my insurance and what's going on. What the heck is going on, this is ridiculous!I've given up... the stress her office staff has put me through is just not worth it. You can do so much better, please clean house, either change out your office staff, or find a way for them to be more efficient please. You have to do something. This is not how you want to run your practice. It leaves a very bad impression on your more
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I was actually pleasantly surprised with this visit! It took me a long time to get the appointment scheduled because no... one answers your phones EVER! After a month, I finally got in, and your staff was warm, friendly, and I was totally impressed! I feel like you will take care of my needs!read more
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It was a nice visit. Happy staff doing all they can do to comfort the patients in a very calming environment. You ask... me they are earned a big gold star on the fridge. My only complaint they didn't give me any more
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I love going to this office. The staff is friendly and helpful. The doctor is great. I am getting the best... neurological tests and treatment I have ever had. The only reason I did not give them a 5 star rating is because it is impossible to reach a live person at the office to reschedule appointments. Every time I have tried to get through to the office it says all people are busy and I am sent to a voicemail. If they could get their phone answering fixed, I would give them a strong 5 more
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Dr. Harney is an excellent Dr. I found him friendly , personable and thorough. I evidently am an unusual case. ... Therefore he spent a Hugh amount of time educating me. He even gave me literature to further explain my condition and how to follow up. This is something you rarely get from your doctors. So I am more than please with my doctor and his more
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Always courteous, professional. The staff is very friendly and always work with you to find the best appointment time.... The care team has been great. Always taking the time to listen to your concerns and to find the best more
Margaret Rowland
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I have been a patient at Lone Star Neurology for several years. Now both my adult daughters also are patients there. I... love Jodie. She is always so prompt whether it is a teleamed call are a visit in the office. She takes the time to explain everything to me and answers all my questions. I am so blessed to have Jodie as my more
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My husband had an accident 5 years ago and Lone Star Neurology has been such a blessing to us with my husbands care.... Jodie Moore is his provider and she is amazing! Jodie is very knowledgeable, caring, and thorough. She takes her time with you, making sure your needs are met and she is happy to answer any questions you may have. Lone Star Neurology’s patients are very lucky to have Jodie providing their care. Thank you Lone Star Neurology and especially Jodie for everything you have done for us. Jodie, you are the best!read more
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Jodie is wonderful. She is very caring and knowledgeable. I have been to over a dozen neurologists, and none were able... to help me as much as they have here. Thanks!read more
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Jodi Moore, nurse practitioner, is amazing. I have suffered from frequent, debilitating headaches for almost 20 years.... She has provided the best proactive and responsive care I have ever received. My quality of life has been greatly improved by her caring approach and tenacity in finding more
Ellie Natsis
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15:41 07 Jan 21
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Matt Morris
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15:39 07 Jan 21
Let me start by saying that I have been coming here for years. Due to my autoimmune disease, I am in this office... once every three weeks for multiple hours at a time. The office is very clean and the staff very friendly. My only complaint would be there communication via phone. They aren't the best at responding if you leave a voicemail and expect a call back. I understand that this is prob just due to the sheer number of alls they receive daily. What I can say I like the best about the office are the people. Bobby who handles my infusions is great. I never have any issues with her setting up my infusions. She is very quick to reply to messages sent via text and if she were to leave then my whole opinion of the office may change. I also enjoy people like Matt, Lauren, and Jodi. I appreciate all that they do for me and without this team I'm not sure I would be as happy as I am to visit the office as frequently as I have to. Please ensure that these folks are recognized as they are what makes my visit to this office so tolerable :).read more
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