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What Is Neuroplasticity And How Does It Work?

Sandeep Dhanyamraju
Medically reviewed by Chaitanya Bonda
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Sandeep Dhanyamraju
Medically reviewed by Chaitanya Bonda

In the complex fabric of the human brain lies a phenomenon that has fascinated neuroscientists and intrigued inquiring minds. It is called neuroplasticity. This fascinating concept offers a glimpse into our brains’ remarkable adaptability and resilience. Neural adaptability is a fascinating journey through the brain’s ability to rewire itself, create new connections and pathways, and ultimately shape our thoughts, behaviors, and experiences.

But what exactly is neuro adaptiveness, and how does it unfold in the intricate networks of our minds? Let’s decipher the mystery of neural adaptability together. How does neuroplasticity work? We will delve deeply into the mechanisms underlying this phenomenon. We will focus on the territory of neuron flexibility. We will reveal the transformative potential it holds in our cognitive evolution.

The adaptability of the brain has no limits. Today, researchers continue to unravel the secrets of human cognition. So, let’s explore neural adaptability and all aspects of this phenomenon together.

What is Neuroplasticity?

Brain flexibility refers to the brain’s remarkable ability to adapt throughout a person’s lifetime. The brain can change its structure and functions in response to environmental influences.

Critical aspects of neuroplasticity include:

  • Structural changes. It refers to physical changes in the structure of the brain. This may include the formation of new neural connections (synapses). It can also be shortening or removing unused links. These changes include changes in the size and shape of neurons.
  • Functional changes. Brain flexibility also includes changes in the active organization of the brain. This means that different parts of the brain can perform new functions. They can also adapt existing tasks in response to learning or injury. For example, if one part of the brain is damaged, another amount can compensate for its functions.
  • Learning and memory. Neuroplasticity plays a critical role in learning and memory. When we learn new information, it often involves the creation of new neural connections. This process allows us to encode and store data in the brain.
  • Restoration and rehabilitation. Neural adaptability is a fundamental principle of neurorehabilitation. For example, people who have suffered brain injuries or strokes can undergo rehabilitation. This can encourage the brain to reset and restore lost functions.
  • Depends on experience. Neuro adaptiveness depends on experience. It is determined by the activities and experiences that a person engages in. The brain’s ability to adapt depends on the specific knowledge it encounters.
  • Developmental plasticity. Neural adaptability is particularly prominent during early brain development. The brain undergoes significant changes in response to the environment during childhood. It forms cognitive and emotional development.

How does neuroplasticity work? Understanding brain flexibility has significant implications in a variety of fields. This is especially important in education, rehabilitation, and neuroscience. This highlights the importance of engaging in lifelong learning. Regular exercise helps keep the brain flexible and adaptable. In addition, it offers hope for recovery and rehabilitation in neurological injuries.

decorative image of the human brain

How Does Neuroplasticity Work?

Brain flexibility is a complex and dynamic process. It involves numerous mechanisms at the cellular and molecular levels. Scientists are still studying the exact mechanisms of this process. But here’s a simplified overview of how neuroplasticity works.

Synaptic adaptiveness forms the basis of neural adaptability.  Neurons transmit information through connections known as synapses. There are two main types of synaptic plasticity:

The process that strengthens synaptic connections is LTP (Long-Term Potentiation). This involves increasing the efficiency of neurotransmitter signaling between neurons.

LTD is the opposite of LTP. This is due to the weakening of synaptic connections.

Neuro adaptiveness also involves structural changes in the brain. These changes may include:

  • dendritic growth;
  • sprouting of axons;
  • synaptic reduction;
  • neurotransmitters;
  • gene expression;
  • hebbian plasticity;
  • environmental and experiential factors;
  • modulation of neurotransmitters.

How does neuroplasticity work? Neural adaptability is a highly adaptive and dynamic process. It allows the brain to rewire itself in response to experience, learning, and environmental factors.

Mechanism of Neuroplasticity

Brain flexibility is also known as brain adaptiveness. This is the mechanism by which the brain reorganizes its structure. There are two main types mechanisms of neuroplasticity:

  • Synaptic plasticity. This includes changes in the strength and efficiency of connections between neurons at synapses. It is essential for learning and memory.
  • Structural adaptiveness. This includes physical changes in the structure of the brain. It can consist of the growth of new neurons (neurogenesis) and the formation of new connections (dendritic branching). Structural plasticity is associated with longer-term changes in response to environmental factors.

Neuroplasticity allows the brain to adapt to new information, recover from injuries, and compensate for deficits. This makes it a fundamental learning, memory, and recovery process after brain injuries.

Biological processes

Several biological processes contribute to neural adaptability:

  • Synaptic plasticity. Such adaptiveness involves changes in the strength and efficiency of synapses. They are the primary connections between neurons. This process includes long-term potentiation (LTP) and long-term depression (LTD). Here, synaptic connections are either strengthened or weakened based on neuronal activity.
  • Structural changes. Neuroplasticity encompasses structural changes in the brain. This may include dendritic growth, axon sprouting, and synaptic shortening. Dendrites grow to increase the surface area for receiving signals. Axons grow new branches to make new connections. Synaptic pruning eliminates weak or unused synapses to improve neural circuits.
  • Neurotransmitters. Chemical messengers in the brain play a key role in neural adaptability. Glutamate, for example, is critical to the LTP process. Changes in neurotransmitter release and receptor sensitivity can affect synaptic strength.
  • Gene expression. Changes in gene expression in neurons are another vital aspect of neuro adaptiveness. Learning and experience can activate or deactivate specific genes. This can lead to new synaptic connections or the strengthening of existing ones.

Synaptic plasticity

Synaptic adaptiveness is the cornerstone mechanism of neuroplasticity. It covers two main types:

  • Long-term potentiation (LTP). LTP involves the strengthening of synaptic connections. This occurs when two neurons are repeatedly and synchronously activated together. This leads to an increase in the efficiency of transmitting signals through the synapse.
  • Long-term depression (LTD). LTD is the opposite of LTP and results in a weakening of synaptic connections. When two neurons rarely fire together, their synapse becomes less effective. This reduces the strength of their bond.

Role of neurons, synapses, and neurotransmitters

Neurons are the basic building blocks of the nervous system. They transmit information using electrical signals. These cells communicate with each other through synapses. Neural adaptability depends on the ability of neurons to adapt and rearrange their connections.

Synapses are connections where neurons exchange information. The adaptiveness of these connections allows the modification of neural circuits. The strengthening or weakening of synapses is essential for learning.

Neurotransmitters are chemical messengers that transmit signals between neurons. They modulate the strength of synapses and play a crucial role in synaptic adaptiveness. Changes in the levels of neurotransmitters contribute to the dynamic nature of neuroplasticity.

Understanding these biological processes provides insight into how the brain adapts to learning, experience, and environmental changes. This knowledge has profound implications for education, rehabilitation, and treatment of neurological diseases.

decorative image of the human brain at black background

Types of Neuroplasticity

There are two main types: structural adaptiveness and synaptic plasticity.

Here’s a table summarizing the different types of neuroplasticity:

Type of Neuroplasticity


Synaptic Plasticity Changes in the strength and efficiency of synaptic connections between neurons.
  • Long-Term Potentiation (LTP)
Strengthening of synapses, enhancing signal transmission.
  • Long-Term Depression (LTD)
Weakening of synapses, reducing signal transmission.
Structural Plasticity Physical changes in brain structure, including the growth of new neurons and the formation of new connections.
  • Neurogenesis
The birth of new neurons, primarily in the hippocampus and certain other brain regions.
  • Dendritic Branching
The growth and branching of dendrites, the receiving ends of neurons, to form new connections.
  • Axonal Sprouting
The extension of axons (nerve cell projections) to form new connections and compensate for damaged ones.
  • Cortical Remapping
Reorganization of sensory and motor maps in the cortex in response to sensory.


Structural Plasticity

This adaptiveness is a fundamental aspect of neural adaptability. It involves physical changes in the structure of the brain. Structural plasticity refers to changes in the physical architecture of the brain itself. Here are the main points about the plasticity of the system:

  • Dendritic growth. Structural plasticity may include the development of new dendritic branches. They are projections of neurons that receive input signals. This growth allows new synapses to form and neural networks to expand.
  • Axon sprouting. Axon sprouting is another aspect of adaptiveness. It involves the formation of new branches on the axons of neurons. In this way, they transmit signals to other neurons. Axon sprouting can create new connections and pathways in the brain.
  • Synaptic pruning. In addition to growth, structural plasticity also encompasses synaptic pruning. This process involves the elimination of weak or unused synapses. Synaptic shortening improves neural circuits. It ensures support for only the most relevant connections. This is crucial for optimizing brain function.
  • Training and adaptation. This adaptiveness plays a crucial role in learning and adaptation. This allows the brain to readjust in response to new experiences. The formation of new connections and the elimination of unnecessary ones enable the brain to adapt.
  • Recovery after injury. Structural plasticity is also essential in the context of brain recovery after injury. This adaptiveness can help compensate for lost function when brain parts are damaged.

Functional Plasticity

This adaptiveness revolves around the brain’s ability to redistribute functions between different areas. Functional plasticity focuses on changes in how neural circuits perform specific tasks. Here are some essential aspects and examples of plasticity:

  • Compensation for brain damage. One of the best-known aspects of functional plasticity is its role in compensating for brain damage. Other parts of the brain can take over the functions of a specific damaged part. This compensation can facilitate recovery and help people regain lost abilities.
  • Language processing. Observers note this adaptiveness in the area of language processing. This works well in cases where the brain lesions affect the language centers. The brain can redistribute language functions to other regions. It allows people to regain or develop language skills through rehabilitation.
  • Sensory adaptation. Plasticity also plays a role in sensory adaptation. For example, brain parts may become more sensitive to auditory or tactile stimuli in people with vision loss. It improves their non-visual sensory perception.
  • Cross-modal adaptiveness. Functional plasticity relates to cross-modal plasticity. One sensory modality (e.g., vision) can compensate for a deficit in another (e.g., hearing). In this scenario, the brain adapts to use the rest of the senses more effectively.
  • Learning and acquiring skills. This adaptiveness is essential for acquiring knowledge. When people learn and practice new knowledge, the brain reorganizes itself. This helps to optimize the neural circuits responsible for this activity. This process allows you to acquire skills over time and increase productivity.
  • Developmental plasticity. This adaptiveness is significant during early brain development. Children’s brains are very adaptive. Functional plasticity allows it to change configuration based on earlier experience.
  • Restoration and rehabilitation. Rehabilitation programs after neurological injuries use this adaptiveness. People can tap into the brain’s ability to reorganize and adapt through exercise. This results in improved motor functions, cognitive skills, and general well-being.

Understanding this adaptiveness highlights the brain’s extraordinary capacity to adapt, learn, and regenerate. This has profound implications for neurorehabilitation, education, and therapy. Understanding the types of neuroplasticity in general is very important.


How does neuroplasticity work? In summary, neural adaptability is an exciting and vital concept in neuroscience. It demonstrates the brain’s extraordinary adaptability and ability to change throughout a lifetime. This cognitive phenomenon covers different types.  We distinguish synaptic adaptiveness, structural plasticity, and functional plasticity among them. Each class offers a unique insight into the dynamic nature of the brain.

Synaptic adaptiveness involves the strengthening and weakening of neuronal connections. It is the basis of learning and memory formation. Structural plasticity emphasizes physical changes in brain architecture. This facilitates adaptation and recovery from injuries. On the other hand, functional adaptiveness highlights the brain’s ability to redistribute functions. This helps to compensate for damage or gain skills.

These forms of adaptiveness highlight the brain’s enormous potential for recovery and adaptation. They have a deep meaning for various spheres of life. As our understanding of brain flexibility continues to deepen, it opens the door to innovative approaches to improve learning, treat neurological diseases, and promote general cognitive well-being. Neuroplasticity remains an exciting frontier in the exploration of the human brain. It promises a bright future in neuroscience and brain-related therapies.

If you need help with diseases of the nervous system, contact Lone Star Neurology!


What are the Types of Neuroplasticity?

Types of neuroplasticity include:

  • synaptic plasticity,
  • structural plasticity,
  • functional plasticity,
  • sensory adaptation,
  • cross-modal plasticity,
  • homeostatic plasticity,
  • metaplasticity,
  • plasticity of development.


Why is Functional Plasticity Important?

Functional plasticity is essential because it allows the brain to reorganize and adapt. This ability is critical to recovery from brain injuries.


Can Neuroplasticity be Enhanced or Hindered?

Yes, neuroplasticity can be both enhanced and slowed down. It can improve through training and exercise. Conversely, aging, stress, and certain neurological diseases can interfere with neuroplasticity.

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Edward Medina
Edward Medina
15:34 30 Jun 22
Just such an amazing staff that makes you feel like part of their family. I’ve been going there for over 5 years now... and each visit I get the very best care and treatments that I have ever received in the 20+ years that I’ve been dealing with severe debilitating migraines. Since i started seeing them the number of my migraines has dropped from 15-20 a month to 2-3 every 3 month. I highly recommend them …they will change your life!read more
Daneisha Johnson
Daneisha Johnson
22:20 19 May 22
Dr. Askari was very kind and explained everything so I could understand. The other staff were nice as well. I would... have gave 5 stars but I was a little taken aback when I checked in and had to pay 600.00 upfront. I think that should have been discussed in a appointment confirmation call or email just so I could have been more
Jean Cooper
Jean Cooper
16:54 29 Apr 22
I love the office staff they are friendly and very helpful. Dr. JODIE is very caring and understanding to your needs... and wants to help you. I will go back. would recommend Dr. Dr. Jodie to other Patients in a heart beat. The team works well more
Linda M
Linda M
19:40 02 Apr 22
I was obviously stressed, needing to see a neurologist. The staff was so patient and Dr. Ansari was so kind. At one... point he told me to relax, we have time, when I was relaying my history of my condition. That helped ease my stress. I have seen 3 other neurologists and he was the only one who performed any assessment tests on my cognitive and physical skills. At one point I couldn't complete two assessments and got upset and cried. I was told, it's OK. That's why you're here. I was truly impressed, and super pleased with the whole experience!read more
Leslie Durham
Leslie Durham
15:05 01 Apr 22
I've been coming here for about 5 years. The staff are ALWAYS friendly and knowledgeable. The Doctors are the absolute... best!! Jodie Moore is always in such a great mood which is a plus when you are already stressed. Highly recommendedread more
Monica Del Bosque
Monica Del Bosque
14:13 25 Mar 22
Since my first post my thoughts have changed here. It's unfortunate. My doctor and PA were great, but the office staff... is horrible. They never call you back when they say they will, they misinform you, they cause you too much stress wondering what's going on, they don't keep you posted. They never answer the phone. At this point I've left four messages in the last week, and I have sent three messages. Twice from their portal and one direct email. No response. My appointment is on Monday morning at 8:30am, no confirmation on my insurance and what's going on. What the heck is going on, this is ridiculous!I've given up... the stress her office staff has put me through is just not worth it. You can do so much better, please clean house, either change out your office staff, or find a way for them to be more efficient please. You have to do something. This is not how you want to run your practice. It leaves a very bad impression on your more
Ron Buckholz
Ron Buckholz
23:32 23 Mar 22
I was actually pleasantly surprised with this visit! It took me a long time to get the appointment scheduled because no... one answers your phones EVER! After a month, I finally got in, and your staff was warm, friendly, and I was totally impressed! I feel like you will take care of my needs!read more
Steve Nabavi
Steve Nabavi
16:28 16 Mar 22
It was a nice visit. Happy staff doing all they can do to comfort the patients in a very calming environment. You ask... me they are earned a big gold star on the fridge. My only complaint they didn't give me any more
Katie Lewis
Katie Lewis
16:10 10 Feb 22
Had very positive appointments with Jodie and Dr. Sheth for my migraine care. Jodie was so fast with the injections and... has so much valuable info. I started to feel light headed during checkout and the staff was SO helpful—giving me a chair, water, and taking me into a private room until I felt better. Highly recommend this practice for migraine patients, they know what they’re doing!!read more
Joshua Martinez
Joshua Martinez
16:02 10 Dec 21
I was scheduled to be checked and just want to say that the staff was fantastic. They were kind and helpful. I was... asked many questions related to what was going on and not once did I feel as though I was being brushed off. The front desk staff was especially great in assisting me. I'm scheduled to go back for a mri and am glad that I'll be going more
Isabel Ivy
Isabel Ivy
21:42 03 Nov 21
I had such a good experience with Lone Star Neurology, Brent my MRI Tech was so awesome and made sure I was very... comfortable during the appointment. He gave me ear plugs, a pillow, leg support and blanket, easiest MRI ever lol 🤣 My 72 hour EEG nurse Amanda was also so awesome. She made sure I was take care of over the 3 days and took her time with the electrodes to make sure it was comfortable for me! Paige was also a huge help in answering all my questions when it came to my test results, and letting me know her honest opinions about how I should go forth with my more
Leslie Luce
Leslie Luce
17:37 20 Oct 21
The professionalism and want to help attitude of this office was present from the moment I contacted them. The follow... up and follow through as well as their willingness to find a way to schedule my dad was above and beyond. We visited two offices in the same day with the same experience. I am appreciative of this—we spend a lot of time with doctors and this was top notch start to more
robert Parker
robert Parker
16:38 16 Apr 21
I love going to this office. The staff is friendly and helpful. The doctor is great. I am getting the best... neurological tests and treatment I have ever had. The only reason I did not give them a 5 star rating is because it is impossible to reach a live person at the office to reschedule appointments. Every time I have tried to get through to the office it says all people are busy and I am sent to a voicemail. If they could get their phone answering fixed, I would give them a strong 5 more
MaryAnn Hornbaker
MaryAnn Hornbaker
00:26 25 Feb 21
Dr. Harney is an excellent Dr. I found him friendly , personable and thorough. I evidently am an unusual case. ... Therefore he spent a Hugh amount of time educating me. He even gave me literature to further explain my condition and how to follow up. This is something you rarely get from your doctors. So I am more than please with my doctor and his more
Roger Arguello
Roger Arguello
03:05 29 Jan 21
Always courteous, professional. The staff is very friendly and always work with you to find the best appointment time.... The care team has been great. Always taking the time to listen to your concerns and to find the best more
Margaret Rowland
Margaret Rowland
01:12 27 Jan 21
I have been a patient at Lone Star Neurology for several years. Now both my adult daughters also are patients there. I... love Jodie. She is always so prompt whether it is a teleamed call are a visit in the office. She takes the time to explain everything to me and answers all my questions. I am so blessed to have Jodie as my more
Susan Miller
Susan Miller
03:01 13 Jan 21
My husband had an accident 5 years ago and Lone Star Neurology has been such a blessing to us with my husbands care.... Jodie Moore is his provider and she is amazing! Jodie is very knowledgeable, caring, and thorough. She takes her time with you, making sure your needs are met and she is happy to answer any questions you may have. Lone Star Neurology’s patients are very lucky to have Jodie providing their care. Thank you Lone Star Neurology and especially Jodie for everything you have done for us. Jodie, you are the best!read more
Windalyn C
Windalyn C
01:32 09 Jan 21
Jodie is wonderful. She is very caring and knowledgeable. I have been to over a dozen neurologists, and none were able... to help me as much as they have here. Thanks!read more
Katie Kordel
Katie Kordel
00:40 09 Jan 21
Jodi Moore, nurse practitioner, is amazing. I have suffered from frequent, debilitating headaches for almost 20 years.... She has provided the best proactive and responsive care I have ever received. My quality of life has been greatly improved by her caring approach and tenacity in finding more
Ellie Natsis
Ellie Natsis
15:41 07 Jan 21
I have had the best experience at this neurologist's office! For over a year I have been receiving iv treatments here... each month and my nurse, Bobbie is beyond wonderful!! She's so attentive, knowledgeable, caring, and detail oriented. She makes an otherwise uncomfortable experience much more pleasant and definitely puts me at ease! She also helps me with my insurance,ordering this specialty medication and dealing with the ordering process which is no easy feat.Needless to say, she goes above a beyond in every way and I'm so grateful to this office and to Bobbie for all they do for me!read more
Matt Morris
Matt Morris
15:39 07 Jan 21
Let me start by saying that I have been coming here for years. Due to my autoimmune disease, I am in this office... once every three weeks for multiple hours at a time. The office is very clean and the staff very friendly. My only complaint would be there communication via phone. They aren't the best at responding if you leave a voicemail and expect a call back. I understand that this is prob just due to the sheer number of alls they receive daily. What I can say I like the best about the office are the people. Bobby who handles my infusions is great. I never have any issues with her setting up my infusions. She is very quick to reply to messages sent via text and if she were to leave then my whole opinion of the office may change. I also enjoy people like Matt, Lauren, and Jodi. I appreciate all that they do for me and without this team I'm not sure I would be as happy as I am to visit the office as frequently as I have to. Please ensure that these folks are recognized as they are what makes my visit to this office so tolerable :).read more
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