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Chronic Tiredness (Asthenic) Syndrome

Medically reviewed by Sandeep Dhanyamraju
Medically reviewed by Sandeep Dhanyamraju

Stress-related illnesses are by far the most common reason for sick leave. When stress persists for too long, there is a risk of developing fatigue syndrome. Treatment for this condition can take a long time, and its precursors must be taken seriously.

What is asthenic syndrome? Fatigue syndrome is the result of long-term chronic stress that lasts at least six months without adequate recovery. Previously, this condition was called burnout and means that the brain suffers from an overload, and stress takes on the signs of illness.

The symptoms of stress are varied. Stress can manifest itself in physical diagnostics such as:

  • back pain;
  • headache;
  • gastrointestinal upset;
  • palpitations;
  • and a weakened immune system. 

It can be difficult to relax and fall asleep even when you are tired. There are feelings of restlessness, anxiety, depression, and trouble concentrating.

The asthenic syndrome can be described in three stages.

  • The first is the prodromal phase, which can cause physical and mental stress, but the person still performs their functions in everyday life. Most people understand that diagnosis is caused by excessive stress and are lifestyle changes. 
  • If you do nothing to correct the situation, you risk entering an acute phase. This phase can last up to several weeks, and the person cannot act at all, which can result in the inability to get out of bed, think clearly, or concentrate. The ability to do several things at the same time disappears. Feelings of despair and panic can arise and become misinterpreted as depression. 
  • The third phase of the asthenic syndrome is the recovery phase. When the sick person eventually gets to their feet but is still very tired, and has difficulty concentrating and remembering. The longer it takes to recover, the more normal a person’s daily life can be. It should be noted that fatigue syndrome always causes increased sensitivity to stress, even when other diagnostics disappear.

symptoms of asthenic syndrome

Symptoms of asthenic syndrome 

Here are some of the symptoms of fatigue syndrome patients may experience:

  • rapid fatigability, weakness, increased irritability, increasing attention disorder, instability of the emotional and mental state
  • headaches that increase and repeat but are not associated with any pathologies
  • progressive decline in performance, forcing people to take psychostimulants and sleeping pills
  • no less typical diagnostic of chronic fatigue is intense and frequent smoking for mental stimulation in the daytime and alcohol intake in the evenings to relieve nervous excitement
  • weight loss or, conversely, with a sedentary lifestyle, the occurrence of obesity of 1-2 degrees
  • the appearance of joint pain, usually in large joints or in the spine
  • increased body temperature, sore throat, enlargement, and soreness of the cervical, occipital, and axillary lymph nodes
  • unexplained muscle weakness, soreness of certain muscle groups (myalgia)
  • emotional depression, apathy, joyless mood.

These signs of asthenic syndrome gradually progress and are usually not attributed to any bodily illness. In addition, clinical examinations do not reveal any objective changes in the body; laboratory studies show that there are no deviations from the norm.

It often happens that disease is the only diagnostic of chronic disease in the body, latent inflammatory processes that are not detected by routine examinations and infection.


Why ask for help? It is essential to follow the warning signals that the body sends and seek help in time. Recovering from asthenic is a difficult and time-consuming process, but the sooner you seek medical attention, the less harm the disease will cause. No one will thank an overworked person for how long they stood before the illness.

If you or your relative is at risk of asthenic syndrome, seek help from a medical center. For acute diagnostic, it is recommended to seek outpatient psychiatry. The doctor will do a physical exam and listen to your story about the discomfort. Blood tests are often done to rule out other conditions.


Is it possible to recover and feel good again? Most people with fatigue recover, although it can take a long time and can leave an increased sensitivity to stress. The sick person must be on sick leave or reduce the load to enable the body to recover. Relaxation exercises, exercise, and good sleep can help. Reduce demands, spend time with friends and family, and do what you love to do.

treatment of fatigue syndrome

Diagnostics and treatment of asthenic syndrome

The most important diagnostic criteria for fatigue syndrome are:

  • The duration of the manifestations of the diagnostic of the disease is six months or more.
  • The absence of other diseases that can cause similar diagnostic.

The asthenic syndrome is characterized by the progression of symptoms, a gradual worsening of the condition. There is currently no objective laboratory data confirming the presence of fatigue. But in the diagnosis process, it is necessary to exclude the presence of chronic foci of inflammation and somatic diseases with similar diagnostic.

How is fatigue treated? The main thing is that the treatment should be comprehensive, which must include:

  • normalization of the regime (alternate rest and physical activity)
  • vitamin therapy (vitamins B1, B6, B12, C)
  • autogenous training or other active methods aimed at normalizing the psycho-emotional background, up to psychotherapy
  • mandatory walking 2-3-hour walks.

The general principles of this disease treatment aim to improve the patient’s lifestyle, improve the functioning of the immune system, and stabilize their psycho-emotional state. A significant part of them can be realized only by the patient themself. The doctor’s task is to convince you of the need to comply with these measures to improve the condition. The measures include:

  • Streamlining the ratio of work and rest, rational physical activity.
  • Diet therapy: normalization of the diet, rational unloading diet.
  • Vitamin therapy, mainly B vitamins.
  • Massage, exercise therapy, hydrotherapy, such as swimming.
  • Rational psychotherapy, autogenous training, group psychotherapeutic methods.
  • Immunocorrectors and / or adaptogens.
  • Ancillary, symptomatic drugs, for example, nootropics, daytime tranquilizers. Pharmacotherapy should be prescribed and monitored by a doctor only.

Modern living conditions lead to the fact that treatment of asthenic syndrome is a need for many people. Chronic fatigue syndrome is usually the result of latent inflammatory processes in the organs and systems of the body, which are not manifested by clinical diagnostic of the disease or pain.

Also, chronic fatigue can result from hormonal disorders, intoxication from chronic inflammatory processes, the presence of chronic infection (viruses, bacteria, protozoa, etc.).

If you notice that you have a diagnosis of fatigue syndrome, its treatment should include:

  • general body massage;
  • segmental massage of the neck area;
  • physiotherapy exercises;
  • autogenic training.

In case of signs of chronic fatigue, it is imperative to do a spinal massage, including elements of manual therapy.

Comprehensive diagnosis and treatment of asthenic syndrome will improve the patient’s condition and return them to good health.


  • How long does chronic fatigue syndrome last?

Chronic fatigue syndrome (CFS) can last up to six months; this is a condition in which a person feels tired and worsens with physical or mental activity but does not improve with rest.

  • What is the best treatment for chronic fatigue syndrome?

In order to determine the most appropriate treatment, you should consult your doctor. Doctors often prescribe over-the-counter pain relievers such as acetaminophen, aspirin, or ibuprofen.

  • Who gets chronic fatigue syndrome?

This syndrome can occur in any person, but most often people aged 40-60 are susceptible to this syndrome. In addition, it is women who are more susceptible to this syndrome.

  • How does fatigue syndrome affect life?

Eighty percent of cases are women, and often not considered at risk by others. They are often passionate and successful at work, take on a lot of family responsibility and always put the needs of others before their own.

  • What are the symptoms of stress?

 Stress can manifest itself in physical diagnostics such as:

  1. back pain;
  2. headache;
  3. gastrointestinal upset;
  4. palpitations;
  5. and a weakened immune system.

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Edward Medina
Edward Medina
15:34 30 Jun 22
Just such an amazing staff that makes you feel like part of their family. I’ve been going there for over 5 years now... and each visit I get the very best care and treatments that I have ever received in the 20+ years that I’ve been dealing with severe debilitating migraines. Since i started seeing them the number of my migraines has dropped from 15-20 a month to 2-3 every 3 month. I highly recommend them …they will change your life!read more
Daneisha Johnson
Daneisha Johnson
22:20 19 May 22
Dr. Askari was very kind and explained everything so I could understand. The other staff were nice as well. I would... have gave 5 stars but I was a little taken aback when I checked in and had to pay 600.00 upfront. I think that should have been discussed in a appointment confirmation call or email just so I could have been more
Jean Cooper
Jean Cooper
16:54 29 Apr 22
I love the office staff they are friendly and very helpful. Dr. JODIE is very caring and understanding to your needs... and wants to help you. I will go back. would recommend Dr. Dr. Jodie to other Patients in a heart beat. The team works well more
Linda M
Linda M
19:40 02 Apr 22
I was obviously stressed, needing to see a neurologist. The staff was so patient and Dr. Ansari was so kind. At one... point he told me to relax, we have time, when I was relaying my history of my condition. That helped ease my stress. I have seen 3 other neurologists and he was the only one who performed any assessment tests on my cognitive and physical skills. At one point I couldn't complete two assessments and got upset and cried. I was told, it's OK. That's why you're here. I was truly impressed, and super pleased with the whole experience!read more
Leslie Durham
Leslie Durham
15:05 01 Apr 22
I've been coming here for about 5 years. The staff are ALWAYS friendly and knowledgeable. The Doctors are the absolute... best!! Jodie Moore is always in such a great mood which is a plus when you are already stressed. Highly recommendedread more
Monica Del Bosque
Monica Del Bosque
14:13 25 Mar 22
Since my first post my thoughts have changed here. It's unfortunate. My doctor and PA were great, but the office staff... is horrible. They never call you back when they say they will, they misinform you, they cause you too much stress wondering what's going on, they don't keep you posted. They never answer the phone. At this point I've left four messages in the last week, and I have sent three messages. Twice from their portal and one direct email. No response. My appointment is on Monday morning at 8:30am, no confirmation on my insurance and what's going on. What the heck is going on, this is ridiculous!I've given up... the stress her office staff has put me through is just not worth it. You can do so much better, please clean house, either change out your office staff, or find a way for them to be more efficient please. You have to do something. This is not how you want to run your practice. It leaves a very bad impression on your more
Ron Buckholz
Ron Buckholz
23:32 23 Mar 22
I was actually pleasantly surprised with this visit! It took me a long time to get the appointment scheduled because no... one answers your phones EVER! After a month, I finally got in, and your staff was warm, friendly, and I was totally impressed! I feel like you will take care of my needs!read more
Steve Nabavi
Steve Nabavi
16:28 16 Mar 22
It was a nice visit. Happy staff doing all they can do to comfort the patients in a very calming environment. You ask... me they are earned a big gold star on the fridge. My only complaint they didn't give me any more
Katie Lewis
Katie Lewis
16:10 10 Feb 22
Had very positive appointments with Jodie and Dr. Sheth for my migraine care. Jodie was so fast with the injections and... has so much valuable info. I started to feel light headed during checkout and the staff was SO helpful—giving me a chair, water, and taking me into a private room until I felt better. Highly recommend this practice for migraine patients, they know what they’re doing!!read more
Joshua Martinez
Joshua Martinez
16:02 10 Dec 21
I was scheduled to be checked and just want to say that the staff was fantastic. They were kind and helpful. I was... asked many questions related to what was going on and not once did I feel as though I was being brushed off. The front desk staff was especially great in assisting me. I'm scheduled to go back for a mri and am glad that I'll be going more
Isabel Ivy
Isabel Ivy
21:42 03 Nov 21
I had such a good experience with Lone Star Neurology, Brent my MRI Tech was so awesome and made sure I was very... comfortable during the appointment. He gave me ear plugs, a pillow, leg support and blanket, easiest MRI ever lol 🤣 My 72 hour EEG nurse Amanda was also so awesome. She made sure I was take care of over the 3 days and took her time with the electrodes to make sure it was comfortable for me! Paige was also a huge help in answering all my questions when it came to my test results, and letting me know her honest opinions about how I should go forth with my more
Leslie Luce
Leslie Luce
17:37 20 Oct 21
The professionalism and want to help attitude of this office was present from the moment I contacted them. The follow... up and follow through as well as their willingness to find a way to schedule my dad was above and beyond. We visited two offices in the same day with the same experience. I am appreciative of this—we spend a lot of time with doctors and this was top notch start to more
robert Parker
robert Parker
16:38 16 Apr 21
I love going to this office. The staff is friendly and helpful. The doctor is great. I am getting the best... neurological tests and treatment I have ever had. The only reason I did not give them a 5 star rating is because it is impossible to reach a live person at the office to reschedule appointments. Every time I have tried to get through to the office it says all people are busy and I am sent to a voicemail. If they could get their phone answering fixed, I would give them a strong 5 more
MaryAnn Hornbaker
MaryAnn Hornbaker
00:26 25 Feb 21
Dr. Harney is an excellent Dr. I found him friendly , personable and thorough. I evidently am an unusual case. ... Therefore he spent a Hugh amount of time educating me. He even gave me literature to further explain my condition and how to follow up. This is something you rarely get from your doctors. So I am more than please with my doctor and his more
Roger Arguello
Roger Arguello
03:05 29 Jan 21
Always courteous, professional. The staff is very friendly and always work with you to find the best appointment time.... The care team has been great. Always taking the time to listen to your concerns and to find the best more
Margaret Rowland
Margaret Rowland
01:12 27 Jan 21
I have been a patient at Lone Star Neurology for several years. Now both my adult daughters also are patients there. I... love Jodie. She is always so prompt whether it is a teleamed call are a visit in the office. She takes the time to explain everything to me and answers all my questions. I am so blessed to have Jodie as my more
Susan Miller
Susan Miller
03:01 13 Jan 21
My husband had an accident 5 years ago and Lone Star Neurology has been such a blessing to us with my husbands care.... Jodie Moore is his provider and she is amazing! Jodie is very knowledgeable, caring, and thorough. She takes her time with you, making sure your needs are met and she is happy to answer any questions you may have. Lone Star Neurology’s patients are very lucky to have Jodie providing their care. Thank you Lone Star Neurology and especially Jodie for everything you have done for us. Jodie, you are the best!read more
Windalyn C
Windalyn C
01:32 09 Jan 21
Jodie is wonderful. She is very caring and knowledgeable. I have been to over a dozen neurologists, and none were able... to help me as much as they have here. Thanks!read more
Katie Kordel
Katie Kordel
00:40 09 Jan 21
Jodi Moore, nurse practitioner, is amazing. I have suffered from frequent, debilitating headaches for almost 20 years.... She has provided the best proactive and responsive care I have ever received. My quality of life has been greatly improved by her caring approach and tenacity in finding more
Ellie Natsis
Ellie Natsis
15:41 07 Jan 21
I have had the best experience at this neurologist's office! For over a year I have been receiving iv treatments here... each month and my nurse, Bobbie is beyond wonderful!! She's so attentive, knowledgeable, caring, and detail oriented. She makes an otherwise uncomfortable experience much more pleasant and definitely puts me at ease! She also helps me with my insurance,ordering this specialty medication and dealing with the ordering process which is no easy feat.Needless to say, she goes above a beyond in every way and I'm so grateful to this office and to Bobbie for all they do for me!read more
Matt Morris
Matt Morris
15:39 07 Jan 21
Let me start by saying that I have been coming here for years. Due to my autoimmune disease, I am in this office... once every three weeks for multiple hours at a time. The office is very clean and the staff very friendly. My only complaint would be there communication via phone. They aren't the best at responding if you leave a voicemail and expect a call back. I understand that this is prob just due to the sheer number of alls they receive daily. What I can say I like the best about the office are the people. Bobby who handles my infusions is great. I never have any issues with her setting up my infusions. She is very quick to reply to messages sent via text and if she were to leave then my whole opinion of the office may change. I also enjoy people like Matt, Lauren, and Jodi. I appreciate all that they do for me and without this team I'm not sure I would be as happy as I am to visit the office as frequently as I have to. Please ensure that these folks are recognized as they are what makes my visit to this office so tolerable :).read more
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